Why Work Here?


Our mission at CTMC is to bridge the gap between the academic research environment, state of the art cell therapy development and manufacturing technology platforms, and leaders in clinical cancer care to enable rapid advancement of novel therapeutics from concept to clinic.

Our joint venture between MD Anderson Cancer Center, the world-renowned cancer center, and Resilience, a network of advanced biopharmaceutical solutions, creates a collaboration of cancer experts and state of the art development and manufacturing technologies. This unique business model has created a biotech-like engine within the prestigious Texas Medical Center so we can bring life-saving medicines more quickly and effectively to patients.


In this new era of precision medicine, we are shaping the direction of cancer treatment by combining the best talent from biotech and academia to create a dynamic and stimulating work environment with opportunities for growth – both personally and professionally. This drive and passion to create life-changing cancer treatments for patients is at the forefront of all that we do.


If you are seeking the next challenge with the desire to contribute to our unified goal of treating patients in their battle with cancer, contact CTMC at: hr@ctmc.com

Job Openings


About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Lead cross-functionally on planning, allocation, receiving, shipping, and procurement on all required cell therapy products.
  • Knowledge of ERP system, implementation, and functionality.
  • Process owner across all clinical sites for shipping and receiving of all Viral Vector, Cell Therapy, and Tissue Culture products.
  • Manage the cGMP and non-GMP receiving departments.
  • Develop inventory strategies that minimize financial impact and develop systems to manage materials across multiple clinical studies.
  • Drive continuous improvement of the supplier management program.
  • Hire, train, develop, direct, mentor, and evaluate team members to accomplish established goals.
  • Implement and review master supplier agreements in collaboration with procurement and legal departments.
  • Develop a strong relationship with internal and external partners.
  • Implement and influence best practices within the supply chain department.
  • Develop and continuously evolve tools and reporting capabilities to identify potential product delivery issues and resolve them in a timely and efficient manner.
  • Objective setting, measurement reporting, organization development, and process improvement in all areas of responsibility.
  • Oversee and recommend the layout and set up of new and existing GMP supply chain operations.
  • Adapts innovative logistic solutions to changing conditions, improving processes and services.
  • Provide work direction and coordinate the schedules and activities of assigned personnel.
  • Assist in training supply chain and materials management personnel in area standard operating procedures and compliance.
  • Create and/or update standard operating procedures as required.
  • Implement and establish supply chain KPIs as required.
  • Other duties as assigned.

Qualifications/Skills

  • Bachelor’s degree in Supply Chain or Business Administration required: Master’s degree preferred or equivalent combination of education and experience.
  • 8+ yr.’s managerial experience in supply chain or materials management, preferably in a cGMP or FDA regulated environment.
  • Meticulous attention to detail required in terms of documentation, following procedural SOPs, and performing functions as it pertains to the Batch Record. 
  • Proficient with Microsoft Office: Word, Excel, and Outlook.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing equipment

Physical Demands-  

  • Occasional standing and walking required.
  • Frequent sitting and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Perform cleaning, documentation, processing, and materials procurement for the manufacturing department.
  • Assist with training staff on proper operations and documentation in cGMP cleanroom facilities. 
  • Operate standard cleanroom equipment: Incubators, BSCs, and Centrifuges. 
  • Operate the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Incubators, Cell Stacks, Cobes, or Lovos.   
  • Develop SOPs for new and incoming equipment.
  • Provide input and assistance in executing training for cleanroom personnel cGMP, best practices and awareness training related to working in a cleanroom environment. 
  • Coordinates with various departments, such as QA, QC, Material Management, Process Development, and Project Management when required to ensure deadlines are met. 
  • Establish a culture of continuous improvement, collaborative spirit, and dedication to safe workplace practices. 
  • Assist support for routine maintenance activities when needed.  
  • Ensure transparent communication with staff, teams, support functions, and site leadership team.   
  • Establish, drive and report key performance indicators in alignment with Cell Therapy Manufacturing and Biologics Development goals. 
  • Other duties as assigned. 

Qualifications/Skills

  • B.S. preferred, or equivalent education and experience.
  • 2+ yr.’s experience with standard cleanroom equipment: Incubators, BSCs, and Centrifuges required.
  • Previous experience with the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Incubators, Cell Stacks, Cobes, or Lovos preferred.
  • Previous experience with technical writing required.
  • Able to understand and follow personnel flows, cleaning procedures, gowning requirements and other procedures defining requirements necessary to ensure cGMP compliant operations of cleanroom facilities. 
  • Meticulous attention to detail in terms of documentation, following procedure SOPs, and performing functions as it pertains to the Batch Record. 
  • Previous experience with manufacturing calculations and conversions using mathematics and critical thinking preferred or ability to learn.
  • Able to provide input to develop new SOPs for new and incoming equipment. 
  • Proficient with Microsoft Office: Word, Excel, and Outlook.
  • Previous GMP Experience preferred.
  • Ability to work a flexible schedule based off business needs.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing equipment

Physical Demands-  

  • Frequent standing, walking, sitting, and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Occasional lifting, pushing, and pulling up to 50 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Follows personnel flows, cleaning procedures, gowning requirements and other procedures defining requirements necessary to ensure cGMP compliant operations of cleanroom facilities. 
  • Assists with training staff on proper operations and documentation in cGMP cleanroom facilities. 
  • Performs or assists in deviation writing, CAPAs, Root Cause Analysis, or Change Controls. Technical writing skills are required. 
  • Uses standard cleanroom equipment: Incubators, BSCs, and Centrifuges. 
  • Uses the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Waves/Xuris, Incubators, Cell Stacks, Cobes, or Lovos.   
  • Provides input and assistance in executing training for cleanroom personnel cGMP, best practices and awareness training related to working in a cleanroom environment 
  • Coordinates with various departments, such as QA, QC, Material Management, Process Development, and Project Management when required to ensure deadlines are met. 
  • Establishes a culture of continuous improvement, collaborative spirit, and dedication to safe workplace practices. 
  • Creates new SOPs for new and incoming equipment. 
  • Assists support for routine maintenance activities.  
  • Ensures transparent communication with staff, teams, support functions, and site leadership team.   
  • Establishes, drives and reports key performance indicators in alignment with Cell Therapy Manufacturing and Biologics Development goals. 
  • Other duties as assigned. 

Qualifications/Skills

  • B.S. preferred; or equivalent combination of education and experience.
  • 5+ yr.’s experience in a related manufacturing environment (cell therapy or biotech) required.
  • Previous GMP Experience required.
  • Previous experience with cell/tissue culture experience and mammalian cell lines required.
  • Previous experience with standard cleanroom equipment: Incubators, BSCs, and Centrifuges preferred. 
  • Previous experience with the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Waves/Xuris, Incubators, Cell Stacks, Cobes, or Lovos preferred.
  • Meticulous attention to detail required in terms of documentation, following procedural SOPs, and performing functions as it pertains to the Batch Record. 
  • Proficient with Microsoft Office: Word, Excel, and Outlook.
  • Ability to work a flexible schedule based off business needs.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing equipment

Physical Demands-  

  • Frequent standing, walking, sitting, and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Occasional lifting, pushing, and pulling up to 50 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Plan, oversee, and participate in the materials management operations and activities to support Production operations team and other internal customers. 
  • Manage the day-to-day assignments of storeroom and offsite warehouse job tasks and monitor completion of required activities. 
  • Receive incoming shipments of non-GMP/GMP materials and equipment following established procedures. 
  • Draft Standard Operational Procedures and Change Controls, as needed. 
  • Dispense temperature sensitive materials as real time needs dictate. 
  • Ensure the department is in a state of GMP compliance. 
  • Prepare for any client driven or internal audits. 
  • Review deviations, as needed.  
  • Submit and follow up on replenishment requisitions for GMP materials. 
  • Prepare and deliver raw materials, samples, finished product, etc. to various departments as needed ensuring proper procedure and temperature range are followed.
  • Maintain accurate inventory of GMP materials by performing accurate dispensing transactions.  
  • Perform, schedule, and verify inventory cycle counts. 
  • Perform accurate ERP and manual inventory transactions. 
  • Track and ensure completion of team projects.
  • Handle final and incoming product shipments. 
  • Communicate inventory discrepancies to supervisor and escalate as necessary. 
  • Capable of performing duties with little to no supervision. 
  • Capable of Cross-training in all areas of the warehouse operations (ie. Receiving, Inventory Management, Kitting, Shipping). 
  • Pick, Pack, and Ship finished product, materials, and equipment as required per established policies and procedures. 
  • Ensure individual employee training is up to date.  
  • Adhere to all safety and GMP procedures and requirements at all times.
  • Keep warehouse operation clean and inspection ready at all times. 
  • Other duties as assigned. 

Qualifications/Skills

  • High school diploma or equivalent required.
  • 5+ yr.’s experience in a related shipping & receiving manufacturing environment (cell therapy or biotech) required.
  • Proficient with Microsoft Office: Word, Excel, and Outlook.
  • Previous GMP Experience required.

Working Conditions, Equipment, Physical Demands

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing & Shipping & Receiving equipment

Physical Demands- 

  • Frequent standing, walking, sitting, and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Occasional lifting, pushing, and pulling up to 50 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

   CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities:

  • Perform line-clearance/ change-over activities.
  • Disposition/ Hold/ Rejection of raw materials, starting material, in-house prepared materials, intermediates, and drug product.
  • Generate and reconcile in-process and Drug Product labels.
  • Review and approve executed documents related to manufacturing operations, QC, and other departments.
  • Generate deviations, CAPAs and Change Controls associated with Quality Operations practices.
  • Review and approve deviations, CAPAs and change controls.
  • Create procedures and practices within Quality Operations to implement company quality standards.
  • Partner with other departments to implement, optimize, review and approve batch records and procedures.
  • Train and motivate employees to Quality Operations procedures and practices to ensure that quality standards are met.

Qualifications/Skills

  • Bachelor’s degree preferably in scientific field.
  • 6+ yr.’s experience in quality assurance operations within biotech or cell therapy manufacturing preferred.
  • Solid understanding of Cell and Gene Therapies.
  • Solid understanding of cGMPs, GLPs and GXPs.
  • Knowledgeable on local and global regulations.
  • Excellent verbal and written communication skills.
  • Excellent interpersonal and customer service skills.
  • Advanced organizational skills and attention to detail.
  • Time management skills with a proven ability to meet deadlines.
  • Demonstrated analytical and problem-solving skills.
  • Previous experience with oversight and leading others within the team.
  • Proficient with Microsoft Office Suite or related software.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment- Computer, printer, facsimile, telephone

Physical Demands-

Prolonged periods of sitting at a desk and working on a computer and must be able to lift to 15 pounds at times. In addition, ability to sterile-gown and perform activities in the manufacturing suite as well as raw material area when applicable.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 

Responsibilities

  • Performs analytical testing on cell and viral therapy products, to verify product quality, purity, and safety. 
  • Accurately perform, analyze, and demonstrate proficiency on the following tests:
    • Automated and manual cell counts and viability
    • Flow cytometry analysis
    • ELISA
    • Molecular assays.
  • Demonstrate aseptic processing of samples for relevant tests.
  • Perform stability testing as scheduled and specified in the stability studies or protocol for cell therapy and viral supernatant products.
  • Follows laboratory’s quality control policies and procedures. 
  • Documents all quality control activities according to SOPs.  
  • Performs and documents equipment maintenance and calibration activities according to SOPs.  
  • Assists in writing new SOPs, and revising SOPs for test methods, equipment maintenance, and general laboratory practices. 
  • Execute daily lab responsibilities and tasks to meet assigned schedule and deadlines. 
  • Perform stability testing as scheduled and specified in the stability studies or protocol for cell therapy and viral supernatant products. 
  • Assist in performing laboratory investigations and OOS and OOT analysis. 
  • Assist in the execution of validation/qualification programs per ICH guidelines, cGMP and cGTP and other applicable standards. 
  • Assist with equipment qualification, validation programs and/or performance qualification programs. 
  • Reference material/standards characterization and trending. 
  • Assist with technology transfer activities. 
  • Assist area management to ensure that the lab is always in a state of readiness for a given area of relevant standards and regulations. 
  • Ship and receive materials and samples to support QC testing and release. 
  • Support inventory management for all QC lab activities. 
  • Review and release raw materials to be used in GMP manufacturing. 
  • Other duties as required. 

Qualifications/Skills

  • Bachelor’s degree in science field required or equivalent combination of education and experience.
  • 2 yr.’s analytical testing in a quality control laboratory including, automated and manual cell counts and viability, flow cytometry analysis, ELISA and molecular assays.
  • Experience with accurate laboratory calculations and conversions.
  • Previous experience with writing SOPs preferred.
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.
  • Able to carry out planned laboratory activities with minimal supervision.
  • Proficient with Microsoft Office (Excel, Outlook, etc.).
  • Able to work flexible work hours to maintain critical testing during manufacturing runs.
  • Capable of working in a fast-paced environment and communicate effectively with a diverse work group.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Scanner
  • Telephone
  • Lab Equipment

Physical Demands-  

  • Frequent sitting, standing, walking
  • Carrying packages and moving bins and boxes, lifting up to 10 lbs.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 

Responsibilities

  • Work specifically on the development of product characterization assays and help establish correlations between clinical outcomes and product/process characteristics of ex vivo T-cell therapeutics.
  • Develop, optimize, and pre-qualify (if needed) analytical methods in various platforms including, flow cytometry, ELISA, qPCR and/or ddPCR.
  • Work closely with process development, apply developed methods to inform in-process characterization (phenotypic and functional) of gene edited cells.
  • Collect and interpret data, prepare development reports, and present results to cross functional project team to provide updates on project status/ progress.
  • Support the development of standard operating procedures, test methods and associated forms, batch records, analytical descriptions, and sampling plans.
  • Adhere to organizational safety, environmental and industrial hygiene procedures, and practices, and actively participate in maintaining and enhancing the safety of the workplace and the laboratories.
  • Apply organizational and creative skills to improve lab operations and workflow efficiencies.
  • Other duties as required.

Qualifications/Skills

  • Ph.D. in a related scientific/engineering field preferred or Masters degree with 6+ years’ experience in a relevant field.
  • Previous experience in Analytical Development or Quality Control, particularly as related to T cell therapies.
  • Demonstrated hands-on experience on the development flow cytometry assays – Designing multiparameter flow assays (5-10 colors) antibody/fluorochrome selection, optimizing staining protocols, developing compensation and gating strategies, method controls, etc. required.
  • Previous experience operating and demonstrate technical knowledge of BD flow cytometers or equivalent
  • Previous experience performing analysis of multiparametric flow data using software such as FlowJo, FCS Express, or others.
  • Previous experience in developing other analytical methods for cell therapy products, e.g., cell-based functional assays, q-PCR/ddPCR assays, is a plus.
  • Strong scientific understanding of the fundamental principles of immuno-oncology.
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.
  • Demonstrated strong communication skills, interpersonal skills, and a superior drive for results.
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff.
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment- Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands-

  • Occasional standing and walking required
  • Frequent sitting, reaching, and computer/keyboard usage
  • Occasional lifting, pushing, and pulling up to 10 lbs. required

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Works specifically on the development of product characterization assays and help establish correlations between clinical outcomes and product/process characteristics of ex vivo T-cell therapeutics.
  • Identify key metrics to help further characterize therapeutic products and identify potential Critical Quality Attributes (CQAs).
  • Develop, optimize, and pre-qualify (if needed) analytical methods in various platforms including, flow cytometry, ELISA, qPCR and/or ddPCR.
  • Work closely with process development, apply developed methods to inform in-process characterization (phenotypic and functional) of gene edited cells.
  • Collect and interpret data, prepare development reports, and present results to cross functional project team to provide updates on project status/ progress.
  • Support the development of standard operating procedures, test methods and associated forms, batch records, analytical descriptions and sampling plans. Act as subject matter expert in the training and transfer of analytical test methods to internal and external collaborators.
  • Act as SME in the training and transfer of analytical test methods to internal and external collaborators.
  • Adhere to organizational safety, environmental and industrial hygiene procedures and practices, and actively participate in maintaining and enhancing the safety of the workplace and the laboratories.
  • Apply organizational and creative skills to improve lab operations and workflow efficiencies.
  • Other duties as required.

Qualifications/Skills

  • Bachelor’s degree in a related field required, Ph.D. in a related scientific/engineering field preferred.
  • 10+ yr.’s of relevant experience in biotech or contract testing organization; or combination of education and experience.
  • Experience in Analytical Development or Quality Control, particularly as related to T cell therapies.
  • Understanding of the FDA Regulatory requirements as related to cellular identity, purity, and potency.
  • Required: Expertise and hands-on experience in the development of multi-parameter flow cytometry assays for the characterization of cell therapy products.
  • Experience in developing other analytical methods for cell therapy products, e.g., cell-based functional assays, q-PCR/ddPCR assays, is a plus.
  • Strong scientific understanding of the fundamental principles of immuno-oncology.
  • Based on scientific understanding of the process, applies GMP requirements to analytical method development, clinical manufacturing, and process/assay transfer activities.
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.
  • Demonstrated strong communication skills, interpersonal skills, and a superior drive for results.
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff.
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.
  • Ability to operate as an effective tactical, as well as strategic thinker.
  • Ability to coach and influence junior level scientists and associates.

Working Conditions, Equipment, Physical Demands

Equipment-

Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands-

  • Occasional standing, walking required
  • Frequent sitting, reaching, and computer/keyboard usage
  • Occasional lifting, pushing, and pulling up to 10 lbs. required

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Manages the accounts payable process including adherence to the internal purchase orders process and ensuring proper support documentation is included all POs and invoices.
  • Manages the accounts receivable process including preparing, posting, verifying, and recording customer payments and transactions related to accounts receivable.
  • Creates invoices according to company practices; submits invoices to customers.
  • Maintains and updates customer files.
  • Performs and/or assist with monthly, quarterly, and annual accounting and closing activities including reconciliations of bank and credit card accounts.
  • Prepares, reviews, and analyzes flux balance sheet and P&L analysis, general ledger activity, contracts, and other analysis as required.
  • Assists with annual audits, creates financial reports/support as necessary, including internal/external reporting requirements.
  • Prepares journal entries as appropriate to ensure general ledger is in conformance with GAAP.

Qualifications/Skills

  • Bachelor’s Degree in accounting or finance required.
  • 2+ yr.’s experience in accounting preferred.
  • Thorough understanding of GAAP; strong research skills.
  • Experience with handling day-to-day accounts payable and accounts receivable process required.
  • Previous experience with monthly, quarterly, annual, and external accounting and reporting responsibilities.
  • Strong attention to detail and adherence to reporting deadlines.
  • Previous experience with accounting software and Microsoft Office (Excel, Outlook, etc.)

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone

Physical Demands-  

  • Prolonged periods of sitting at a desk and working on a computer 

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

     CTMC (Cell Therapy Manufacturing Center), a joint venture between Resilience and MD Anderson Cancer Center, is a first-of-its-kind biotech located in the world-renowned Texas Medical Center created to accelerate cell therapies moving from research to patients. CTMC develops and manufactures cell therapies invented at MD Anderson, as well as biotechs, including a variety of modalities such as CAR-T, TIL, ETC and TCR-T.  We aim to file 4 INDs in the first 12 months as we work closely with MDACC research and clinical faculty to bring impactful cell therapies to cancer patients. Our partnership with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in their first two years gives CTMC access to advanced technology and processes and enables us to stay at the cutting edge of biomanufacturing practices. Through the capabilities within CTMC and our alliance with MD Anderson Cancer Center and National Resilience, we co-develop cell therapy products with biotech companies and help them industrialize and accelerate their innovative therapeutics to reach the clinic quicker and ultimately maximize patient impact.    

     CTMC is housed in a state-of-the-art 60,000sqft development and manufacturing facility in the Texas Medical Center with an integrated team of 75 industry veterans and scientists with a depth of cell therapy expertise.  The unique structure of our joint venture with two highly established partners gives the organization financial stability and a long-term horizon, despite the current environment of funding uncertainty in the biotech field.  Our broad scope and novel corporate structure allow employees a plethora of development opportunities for members of our team.  We are passionate about aggressively bringing life-saving cures to patients and achieving it through a cohesive team-first culture and balanced work-life environment for our staff.  If you feel you can contribute to our mission and be part of a newly imagined biotech, we welcome your application. 


Responsibilities

  • Performs all activities related to incoming material receipt including inspection, documentation, hands-on handling, and oversight of the manufacture of cell therapy products for clinical studies, working the GMP cleanroom environment.  
  • Operates processing equipment commonly utilized in cell therapy or blood processing laboratories (examples COBE 2991, CliniMACS Prodigy, and Lovo).  
  • Authors SOP and batch record documents within the QMS system.  
  • Assists in the setup of related GMP materials, spec sheets, CofAs, etc.   
  • Assists in the hiring and training of manufacturing associates to work in the GMP environment.  
  • Plans staff availability and schedule manufacturing operations for maximal efficiency.  
  • Coordinates process and cleaning validation requirements for specified products.  
  • Coordinates with various departments, such as QA, QC, Material Management, Process Development, and Project Management when required to ensure deadlines are met. 
  • Establishes a culture of continuous improvement, collaborative spirit, and dedication to safe workplace practices. 
  • Creates new SOPs for new and incoming equipment. 
  • Assists support for routine maintenance activities.  
  • Ensures transparent communication with staff, teams, support functions, and site leadership team.   
  • Establishes, drives, and reports key performance indicators in alignment with Cell Therapy Manufacturing and Biologics Development goals. 
  • Other duties as assigned. 

Qualifications/Skills

  • BS required or equivalent combination of education and experience.
  • 7+ yr.’s experience in a related manufacturing environment (cell therapy or biotech) required.
  • 1+ yr.’s operating at a supervisor level or above.
  • Previous experience with standard cleanroom equipment: Incubators, BSCs, and Centrifuges preferred. 
  • Previous experience with the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Waves/Xuris, Incubators, Cell Stacks, Cobes, or Lovos preferred.
  • Meticulous attention to detail required in terms of documentation, following procedural SOPs, and performing functions as it pertains to the Batch Record. 
  • Previous experience quthoring and revising SOPs and batch records preferred.
  • Proficient with Microsoft Office: Word, Excel, and Outlook.
  • Previous GMP Experience required.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing equipment

Physical Demands-  

  • Frequent standing, walking, sitting, and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Occasional lifting, pushing, and pulling up to 50 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now