Why Work Here?


Our mission at CTMC is to bridge the gap between the academic research environment, state of the art cell therapy development and manufacturing technology platforms, and leaders in clinical cancer care to enable rapid advancement of novel therapeutics from concept to clinic.

Our joint venture between MD Anderson Cancer Center, the world-renowned cancer center, and Resilience, a network of advanced biopharmaceutical solutions, creates a collaboration of cancer experts and state of the art development and manufacturing technologies. This unique business model has created a biotech-like engine within the prestigious Texas Medical Center so we can bring life-saving medicines more quickly and effectively to patients.


In this new era of precision medicine, we are shaping the direction of cancer treatment by combining the best talent from biotech and academia to create a dynamic and stimulating work environment with opportunities for growth – both personally and professionally. This drive and passion to create life-changing cancer treatments for patients is at the forefront of all that we do.


If you are seeking the next challenge with the desire to contribute to our unified goal of treating patients in their battle with cancer, contact CTMC at: hr@ctmc.com

Job Openings


About CTMC 

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients. 

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results. 

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 75 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission. 

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.


Responsibilities: 

  • Foster, lead and embed a strong culture of Quality throughout the organization. 
  • Lead the development, deployment and maintenance of programs, processes, and methods to ensure high quality products and compliance with cGMPs, including operational excellence, training, and effective documents controls. 
  • Provide guidance and support activities to ensure manufacturing facilities and support areas comply with applicable regulations and industry best standards. 
  • Develop and implement best practice quality improvement programs, policies, procedures, and processes. 
  • Lead and participate in projects within the organizations objectives and project timelines and participate in cross-functional projects as the quality subject matter expert. 
  • Collaborate with other leaders across the organization and assist in the continuous improvement.  
  • Represent quality assurance at various projects and technical meetings, as needed. 
  • Manage key quality metrics and resources to ensure compliant disposition of materials and cell therapy products. 
  • Monitor key quality indicators to identify potential risks and for supporting continuous improvement.   
  • Prepare and present periodic management updates on Department activities to Leadership. 
  • Train and motivate employees to Quality Service procedures and practices to ensure that quality standards are met. 
  • Manage a team of quality professionals to goal oriented tasks.
  • Assist in the recruiting process.
  • Other duties as required.

Qualifications/Skills

  • Bachelor’s degree in a scientific field.
  • 12+ yrs. related experience in manufacturing processes, QA, Operational Excellence and Training combined.
  • 6+ yrs. managerial experience, preferably within QA.
  • Understanding of Cell and Gene Therapies.
  • Demonstrate expertise in multiple QA related areas; SME in specific areas related to systems.
  • Understanding of cGMPs, GLPs.
  • Knowledge of local and global regulations.
  • Excellent verbal and written communication skills.
  • Excellent interpersonal and customer service skills.
  • Excellent organizational skills and attention to detail.
  • Excellent time management skills with a proven ability to meet deadlines.
  • Strong analytical and problem-solving skills.
  • Strong supervisory and leadership skills.
  • Proficient with Microsoft Office Suite or related software.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands: 

Equipment- Computer, printer, fax, and telephone.

Physical Demands- Prolonged periods of sitting at a desk and working on a computer and must be able to lift up to 15 pounds at times. In addition, ability to sterile-gown and perform activities in the manufacturing suite as well as raw material area when applicable. 

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC 

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.   

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.   

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of over 80 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.   

At CTMC, we value our employees and offer a variety of development opportunities within our organization. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.  

Role Summary

CTMC is currently in search of an Associate II, Process Development with a strong interest in Cell Therapy to become an integral part of our dynamic Process Development team. In this position, you will play a key role as a team member within our CAR-T and/or TIL groups. The main role focus will be on executing experiments that provide the foundation for protocols aimed towards clinical applications.

This role presents an exciting opportunity to collaborate closely with a highly skilled ensemble of industry professionals and scientists.   The successful candidate will work with cutting-edge equipment and advanced techniques to assist with the development and optimization of CAR-T and TIL therapies that aim to revolutionize the treatment of both solid and hematological cancers. 

Responsibilities

  • Support the execution of cell therapy process development studies for process understanding and optimization. 
  • Perform planned experimental work, including but not limited to cell culture, viral transduction, and cryopreservation associated with the projects. Develops technical expertise with T-cell manufacturing processes.
  • Learn and train on new equipment and protocols, including automated and semi-automated systems.
  • Assist with training of manufacturing staff on new protocols being introduced into the GMP space.
  • Maintain accurate and up to date records of laboratory activities using electronic laboratory notebooks.
  • Assist in drafting and editing of manufacturing batch records and technical reports.
  • Assist with shipments of process development samples.
  • Provide written or verbal technical support including protocols or slide decks as needed. May be asked to present to internal lab meetings.
  • Maintain and order stocks lab supplies and reagents, as well as perform other lab organization duties.
  • Collaborate effectively with members of the viral vector and cell therapy process development and analytical development teams.
  • Other duties as required.

Qualifications/Skills

  • Bachelor’s degree in related scientific / engineering field. 
  • 1+ yr.’s. of relevant experience required, 2+ yr.’s preferred or combination of education and relevant experience comprising of process development of cellular therapies or manufacturing which may include viral vectors and / or other biologics modalities.
  • Excellent aseptic technique required.
  • Experience with accurate laboratory calculations and conversions required.
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team. 
  • Demonstrated strong communication skills, interpersonal skills, and a superior drive for results.
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with scientists and other associates.
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills. 
  • Able to carry out planned laboratory activities under supervision.
  • Able to work a flexible schedule including some weekend and holiday work as needed.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office and laboratory environment. The nature of the work may require occasional work outside regular working hours or on weekends. The incumbent in this position will use the following equipment and shall have the following physical demands: 

Equipment-

  • Computer
  • Printer
  • Scanner
  • Telephone
  • Lab Equipment

Physical Demands-  

  • Frequent sitting, standing, walking.
  • Carrying packages and moving bins and boxes, lifting up to 10 lbs.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC 

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients. 

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results. 

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 75 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission. 

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.


 Responsibilities

  • Learn and observe the execution of different state-of-the-art cell based or molecular biology techniques which are typically used in the development of cell therapies.  
  • Maintains cultures of primary T cells and cancer cell lines with proper documentation.  
  • Performs T cell-based assays such as IFNg ELISA. 
  • Performs genomic DNA extractions to support molecular assays. 
  • Support management of assay reagent inventory as well as other support tasks laid out by their supervisor. 
  • Participates in lab meetings and other collaborative activities.  
  • Showcases achievements/learnings with a presentation at the conclusion of internship to the broader development team. 
  • Other duties as required.

Qualifications/Skills

  • High School Diploma required; enrollment in a minimum Bachelor’s degree program in a relevant field preferred.
  • Previous laboratory experience preferred.
  • Able to learn testing procedures and work utilizing standard operating procedures.
  • Able to work in a fast-paced environment.
  • Demonstrated ability to be nimble, collaborative, and eager to contribute.
  • Good communication skills.
  • Proficient with MS Office (Excel, Outlook, etc.).

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment- Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands- 

  • Occasional standing and walking required
  • Frequent sitting, reaching, and computer/keyboard usage
  • Occasional lifting, pushing, and pulling up to 10 lbs. required

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC 

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients. 

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results. 

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 75 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission. 

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.

Responsibilities

Summer Internship in the PD cell therapy group: 

The PD intern will be exposed to T-cell therapy drug development in industry and learn about the different modalities and their applications. Over the course of the internship, the candidate will: 

  • Observe and discuss the different T-cell expansion processes required for T-cell therapy drugs in development at CTMC with his team members.
    1. observe hands-on cell therapy process development work with mentors in the laboratory as a learning tool, and eventually participate with execution. 
    2. become knowledgeable on the processes observed and be able to discuss the different approaches with the team in group meetings.   
  • Become familiar with aseptic technique and perform contamination-free cell culture.
    1. training on aseptic technique after the observation phase. 
    2. successfully perform processes requiring aseptic technique.  
  • Train on the use of various cell processing devices and equipment
    1. train on multiple devices used in cell therapy production, including automated and semi-automated cell processing devices. 
    2. following training, the candidate will be expected to be able to independently operate equipment and be able to understand the basic mechanisms of operation for the equipment.  
  • Participating in advancement of project by assisting the team.
    1. post-observation phase: the candidate is expected to add value to the team by contributing to the ongoing work to the extent of their capacity.  
    2. continuous learning of new skills under the team’s guidance 
    3. present their work at weekly team meetings.  
  • Potential to carry a small study independently and within the scope of a larger project’s activities.
    1. If the candidate shows great understanding of the processes and the ability of doing autonomous works, the candidate could be given a small study to perform independently (or assisted) under the guidance of the team or the designated mentor.  

Qualifications/Skills

  • High School Diploma required; enrollment in a minimum second year Bachelor’s degree program in a relevant field preferred.
  • Desire to learn cell therapy development.
  • Previous laboratory experience preferred.
  • Able to be a great team player.
  • Able to learn testing procedures and work utilizing standard operating procedures.
  • Able to work in a fast-paced environment.
  • Demonstrated ability to be nimble, collaborative, and eager to contribute.
  • Good communication skills.
  • Proficient with MS Office (Excel, Outlook, etc.).

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment- Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands- 

  • Occasional standing and walking required
  • Frequent sitting, reaching, and computer/keyboard usage
  • Occasional lifting, pushing, and pulling up to 10 lbs. required

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC 

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.  

 In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.  

 Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of over 80 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.

  At CTMC, we value our employees and offer a variety of development opportunities within our organization. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission. 


Responsibilities

  • Performs analytical testing on cell and viral therapy products, to verify product quality, purity, and safety. 
  • Accurately perform, analyze, and demonstrate proficiency on the following tests:
  1. Molecular PCR assays; Vector Copy Number (VCN), Replication Competent Retrovirus (RCR), and Mycoplasma testing using qPCR and ddPCR technology.
  2. Automated and manual cell counts and viability.
  3. Flow cytometry analysis
  • Demonstrate aseptic processing of samples for relevant tests.
  • Follows laboratory’s quality control policies and procedures. 
  • Documents all quality control activities according to SOPs.  
  • Performs and documents equipment maintenance and calibration activities according to SOPs.  
  • Assists in writing new SOPs, and revising SOPs for test methods, equipment maintenance, and general laboratory practices. 
  • Execute daily lab responsibilities and tasks to meet assigned schedule and deadlines. 
  • Perform stability testing as scheduled and specified in the stability studies or protocol for cell therapy and viral supernatant products. 
  • Assist in performing laboratory investigations and OOS and OOT analysis. 
  • Assist in the execution of validation/qualification programs per ICH guidelines, cGMP and cGTP and other applicable standards. 
  • Assist with equipment qualification, validation programs and/or performance qualification programs. 
  • Reference material/standards characterization and trending. 
  • Assist with technology transfer activities. 
  • Assist area management to ensure that the lab is always in a state of readiness for a given area of relevant standards and regulations. 
  • Ship and receive materials and samples to support QC testing and release. 
  • Support inventory management for all QC lab activities. 
  • Review and release raw materials to be used in GMP manufacturing. 
  • Maintain laboratory upkeep and organization.
  • Other duties as required. 

Qualifications/Skills

  • Bachelor’s degree in science field required or equivalent combination of education and experience.
  • 3 yr.’s analytical testing in a quality control laboratory including molecular assays, automated and manual cell counts and viability, flow cytometry analysis and ELISA.
  • Demonstrate expertise for one or more assay categories.
  • Experience with accurate laboratory calculations and conversions.
  • Previous experience with writing SOPs preferred. 
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team. 
  • Able to carry out planned laboratory activities with minimal supervision.
  • Shows initiative to take on additional responsibility.
  • Proficient with Microsoft Office (Excel, Outlook, etc.).
  • Able to work flexible work hours to maintain critical testing during manufacturing runs.
  • Capable of working in a fast-paced environment and communicating effectively with a diverse work group.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Scanner
  • Telephone
  • Lab Equipment

Physical Demands-  

  • Frequent sitting, standing, walking.
  • Carrying packages and moving bins and boxes, lifting up to 10 lbs.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC

   CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 75 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.


Responsibilities

  • Develop robust processes of formulation, fill and finish, and cryopreservation for chimeric antigen receptor T (CAR T) and Tumor-Infiltrating Lymphocytes (TIL) cell products.
  • Design and execute studies on formulation, fill/finish, and cryopreservation of candidate cell therapy product.
  • Evaluate new cryobiological technologies. 
  • Implement process advancements for scaling-up and introduction into a GMP manufacturing environment.
  • Lead technology transfer activities and training manufacturing staff on new processes and equipment,
  • Monitor process performance during clinical manufacturing via data tracking, trending, and analysis.
  • Design and conduct experiments in development laboratory to support process changes, generate process robustness data, and/or resolve manufacturing non-conformances.
  • Draft technical documents including development reports, process descriptions, risk assessments, SOPs, MBRs, and regulatory filing sections.
  • Act as internal expert and maintain state-of-the-art knowledge in the field of cellular cryopreservation and cryobiology.
  • Other duties as assigned.

Qualifications/Skills

  • Ph.D. in a related scientific/engineering field required.
  • 1+ years’ experience in a related field, preferably in the biotech industry or equivalent combination of education and experience.
  • Strong knowledge and hands-on experience with cell therapy process development and cryopreservation; cell therapy experience required.
  • Highly desired experience:

-Formulation science experience with cryoprotectant additives.

-Demonstrated aseptic cell handling skills.

-Experience working in or supporting a cGMP-regulated environment.

-Hands-on experience with common cell therapy laboratory equipment and technology platforms

  • Familiarity with the following is a plus:

-solid background in cell therapy manufacturing processes

  • Proficient with MS Office (Excel, Outlook, etc.) and statistical software (Prism, JMP).
  • Strong scientific understanding of the fundamental principles of cryopreservation and cell therapy.
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.
  • Demonstrated strong communication skills, interpersonal skills, and a superior drive for results.
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff.
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in a lab and office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands- 

  • Occasional standing and walking required.
  • Frequent sitting, reaching, and computer/keyboard usage.
  • Occasional lifting, pushing, and pulling up to 10 lbs. required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients. 

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results. 

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 75 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission. 

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.


Responsibilities

  • Manage all Viral Vector projects while successfully coordinating across multiple functional groups to ensure deadlines are met. 
  • Prepare and deliver reports and data to internal or external parties.
  • Subject Matter Expert regarding Viral Vector equipment: Incubators, CellStacks, Kros-Flo, Chromatography skids.
  • Draft and revise a training program to ensure GMP compliance and operational compliance with viral vector processes.    
  • Draft, revise, and implement high level Standard Operating Procedures to govern the use of GMP facilities.
  • Perform gap analysis programs for new processes and successfully complete Tech Transfers under required deadlines.
  • Establish a culture of continuous improvement, collaborative spirit, and dedication to safe workplace practices. 
  • Perform employee scheduling for multiple simultaneous processes in terms of communication and training standards to work towards a zero-deviation environment.  
  • Provide support on IND filings when needed.
  • Establish, drive and report key performance indicators in alignment with Cell Therapy Manufacturing and CTMC goals in partnership with other departments.
  • Conduct thorough investigations in case of deviations on process excursions in close coordination with all relevant functions.
  • Other duties as assigned.  

Qualifications/Skills

  • Bachelor’s degree in a scientific field; or equivalent combination of education and experience.
  • 12+ yr.’s experience in a related manufacturing environment (viral vector, cell therapy, or biotech). Experience with CAR-T or TIL Cell Therapies, a plus.
  • 5+ yr.’s previous experience in a management or supervisory role.
  • Strong knowledge of GMP Practices and FDA requirements required.
  • Proficient with manufacturing calculations and conversions.
  • Previous experience with standard cleanroom equipment: Incubators, BSCs, and Centrifuges preferred. 
  • Previous experience with a QMS system, such as Veeva, TrackWise, or Master Control required.
  • Previous experience with preparation and delivery of reports/data to internal or external parties.
  • Able to lead and grow an organization of 5+ personnel.
  • Previous experience with developing employees, giving employee reviews, etc. 
  • Previous experience authoring and revising SOPs and batch records required.
  • Strong organizational and time management skills. 
  • Proficient with Microsoft Office: Word, Excel, and Outlook.
  • Previous experience with technical writing required.
  • Able to understand and follow personnel flows, cleaning procedures, gowning requirements and other procedures defining requirements necessary to ensure cGMP compliant operations of cleanroom facilities. 
  • Able to troubleshoot cell processing operations and equipment.
  • Able to establish new systems or processes to achieve manufacturing goals and reduce workplace error.
  • Able to take on ancillary cross-functional projects and drive to completion.
  • Meticulous attention to detail in terms of documentation, following procedure SOPs, and performing functions as it pertains to the Batch Record.
  • Able to work a flexible schedule including nights, weekends, and holidays with short advance notice.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office and clean room environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing equipment

Physical Demands-  

  • Frequent standing, walking, sitting, and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Occasional lifting, pushing, and pulling up to 50 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

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