Why Work Here?


Our mission at CTMC is to bridge the gap between the academic research environment, state of the art cell therapy development and manufacturing technology platforms, and leaders in clinical cancer care to enable rapid advancement of novel therapeutics from concept to clinic.

Our joint venture between MD Anderson Cancer Center, the world-renowned cancer center, and Resilience, a network of advanced biopharmaceutical solutions, creates a collaboration of cancer experts and state of the art development and manufacturing technologies. This unique business model has created a biotech-like engine within the prestigious Texas Medical Center so we can bring life-saving medicines more quickly and effectively to patients.


In this new era of precision medicine, we are shaping the direction of cancer treatment by combining the best talent from biotech and academia to create a dynamic and stimulating work environment with opportunities for growth – both personally and professionally. This drive and passion to create life-changing cancer treatments for patients is at the forefront of all that we do.


If you are seeking the next challenge with the desire to contribute to our unified goal of treating patients in their battle with cancer, contact CTMC at: hr@ctmc.com

Job Openings


About CTMC 

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.   

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.  

 Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of over 80 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.  

At CTMC, we value our employees and offer a variety of development opportunities within our organization. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission. 


 Responsibilities

  • Perform cleaning, kitting, documentation, processing, and materials procurement for the manufacturing department.
  • Request and prepare materials for manufacturing operations while maintaining proper inventory levels in the cleanroom at all times.
  • Maintain aseptic technique during processing to ensure quality and integrity of cellular drug products.
  • Execute master batch production records in a timely manner and maintain accurate documentation with FDA’s Good Manufacturing Practices.
  • Perform error free calculations, including but not limited to cell doses, dilutions, and total cell count or total viable cell count numbers.
  • Provides input and assistance in executing training for cleanroom personnel cGMP, best practices and awareness training related to working in a cleanroom environment.
  • Provide input on manufacturing process optimization based on working knowledge and understanding of project for which individual is an SME.
  • Operate standard cleanroom equipment: Incubators, BSCs, and Centrifuges.
  • Operate the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Waves/Xuris, Incubators, Cell Stacks, Cobes, or Lovos.   
  • Develop and create new SOPs for new and incoming equipment.
  • Troubleshoot cell processing operation and equipment, escalating issues as needed.
  • Assist in SOP revisions and creating new batch records for tech transfers.
  • Perform or assist in deviation writing, CAPAs, Root Cause Analysis, or Change Controls. 
  • Coordinate with various departments, such as QA, QC, Material Management, Process Development, and Project Management when required to ensure deadlines are met. 
  • Train junior level Associates on manufacturing processes; act as SME.
  • Assist with training staff on proper operations and documentation in cGMP cleanroom facilities; including but not limited to Gowning Qualifications and Aseptic Process Simulation for new hires.
  • Establish a culture of continuous improvement, collaborative spirit, and dedication to safe workplace practices. 
  • Assist with support for routine maintenance activities.
  • Ensure transparent communication with staff, teams, support functions, and site leadership team.
  • Meet and reports key performance indicators in alignment with Cell Therapy Manufacturing and CTMC goals. 
  • Other duties as assigned. 

Qualifications/Skills

  • Bachelor’s degree in scientific field, or equivalent education and experience.
  • 3+ yr.’s experience in a related manufacturing environment (cell therapy or biotech) required.
  • 3+ yr.’s experience with standard cleanroom equipment: Incubators, BSCs, and Centrifuges required. 
  • Previous experience with one or more of the following Cell Therapy equipment: CliniMacs Prodigies, G-Rexes, Waves/Xuris, Incubators, Cell Stacks, Cobes, or Lovos preferred. 
  • Proficient with Microsoft Office: Word, Excel, Outlook, PowerPoint, and Teams.
  • Previous GMP Experience required.
  • Previous experience performing accurate calculations and lab measurements required.
  • Previous experience with technical writing required.
  • Able to understand and follow personnel flows, cleaning procedures, gowning requirements and other procedures defining requirements necessary to ensure cGMP compliant operations of cleanroom facilities. 
  • Able to troubleshoot cell processing operations and equipment.
  • Meticulous attention to detail in terms of documentation, following procedure SOPs, and performing functions as it pertains to the Batch Record.
  • Able to train and lead junior level Associates on all aspects of the manufacturing process for which the individual is an SME.
  • Able to work a flexible schedule including nights, weekends, and holidays with short advance notice.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office and clean room environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Facsimile
  • Telephone
  • Manufacturing equipment

Physical Demands-  

  • Frequent standing, walking, sitting, and reaching required.
  • Frequent lifting up to 10 lbs. required.
  • Occasional lifting, pushing, and pulling up to 50 lbs. required.
  • Frequent use of computer/keyboard required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 93+ industry veterans and academic scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.

Responsibilities

  • Leads and oversees process development projects assigned by leadership with the goal to improve manufacturing processes for CAR-T, TILs and other T-cell therapies.  
  • Assess manufacturing processes supplied by prospective partner companies for suitability for GMP manufacture and identify any gaps.
  • Design, plan and oversee execution of the experimental plans to optimize/refine manufacturing process for T-cell therapeutics.
  • Manage, coach and develop reports.
  • Participate in hands-on project execution as needed, serve as a resource/subject matter expert for the technical team. Assign and manage reports to complete projects and trains junior team members on T-cell therapy processing. Troubleshoot technical issues with the team as they arise in the lab and share best practices and lessons learned. 
  • Develop processes in alignment with the latest FDA guidance and regulations applicable to the generation and quality monitoring of T-cell therapy products to ensure rapid translation of developed procedures in the GMP lab. 
  • Drive internal tech transfers from process development to manufacturing team. Lead the team to produce a complete draft of the manufacturing batch record aligned with CTMC quality standards at the conclusion of the development campaign and trains manufacturing operators in preparation for the engineering runs.
  • Provide technical assessment of various new cell therapy technologies and make recommendations on process decisions for GMP implementation. 
  • Coordinate execution of project deliverables to meet timelines. 
  • Maintain current knowledge of the T-cell manufacturing field and introduce relevant materials to continuously improve the current processes.  
  • Maintain thorough accurate, legible, and organized written and electronic records, including use of electronic lab notebook. 
  • Author or review protocols, technical reports and draft manufacturing batch records. Author or review process-related CMC sections of IND applications. Train team members on authorship of said documents and eventually delegates authorship.
  • Prepare scientific presentations to report on the status of the work performed in the laboratory and speak in front of a group of scientists and leadership that may include external partners .
  • Communicate effectively within the company with members of own team or other departments such as manufacturing, analytical development, quality control, regulatory affairs and project management.  
  • Interface with appropriate internal and external key stakeholders, work with other functions / departments to achieve project objectives.
  • Other duties as assigned.

Qualifications/Skills

  • Ph.D. in a related scientific/engineering field.
  • 10+ yrs. experience in PD laboratory operations developing processes on various cell manufacturing platforms and closed systems for the development of T-cell therapy products.   
  • Strong knowledge in T-cell biology.  
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.  
  • Demonstrated strong communication skills, interpersonal skills and a superior drive for results. 
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff. 
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.  
  • Able to operate as an effective tactical, as well as strategic thinker. 
  • Able to coach and influence junior level scientists and associates.  
  • Flexible to work outside of normal business hours (nights, weekends) as needed.
  • Proficient with Microsoft Office Suite or related software.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office and lab environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer, printer, telephone
  • Laboratory equipment

Physical Demands-

  • Occasional standing and walking required.
  • Frequent sitting, reaching, and computer/keyboard usage.
  • Occasional lifting, pushing, and pulling up to 10 lbs. required.

The above job description is an overview of the functions and requirements for this position. This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

Apply Now

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients. 

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results. 

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 75 industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission. 

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.


Responsibilities

  • Perform analytical testing on cell and viral therapy products, to verify product quality, purity, and safety. 
  • Accurately perform, analyze, and demonstrate proficiency on the following tests:
  • Automated and manual cell counts and viability
  • Flow cytometry analysis 
  • ELISA
  • Molecular assays (PCR, ddPCR)
  • Participate as an analyst in MQ activities including authoring SOPs and FRMs.
  • Demonstrate aseptic processing of samples for relevant tests.
  • Follow laboratory’s quality control policies and procedures. 
  • Document all quality control activities according to SOPs.  
  • Perform and documents equipment maintenance and calibration activities according to SOPs.  
  • Assist in writing new SOPs, and revising SOPs for test methods, equipment maintenance, and general laboratory practices. 
  • Execute daily lab responsibilities and tasks to meet assigned schedule and deadlines. 
  • Perform stability testing as scheduled and specified in the stability studies or protocol for cell therapy and viral supernatant products. 
  • Assist in performing laboratory investigations related to OOS/ OOT/Abnormal analysis. 
  • Assist in the execution of validation/qualification programs per ICH guidelines, cGMP and cGTP and other applicable standards. 
  • Assist with equipment qualification, validation programs and/or performance qualification programs. 
  • Reference material/standards characterization and trending. 
  • Assist with technology transfer activities. 
  • Assist area management to ensure that the lab is always in a state of readiness for a given area of relevant standards and regulations. 
  • Ship and receive materials and samples to support QC testing and release. 
  • Support inventory management for all QC lab activities. 
  • Review and release raw materials to be used in GMP manufacturing. 
  • Maintain laboratory upkeep and organization.
  • Train junior members of the team on medium-high complexity assays.
  • Other duties as required. 

Qualifications/Skills

  • Bachelor’s degree in science field required or equivalent combination of education and experience.
  • 5 yr.’s analytical testing in a quality control laboratory including, automated and manual cell counts and viability, flow cytometry analysis, ELISA and molecular assays.
  • Serve as an SME one or more assay categories.
  • Experience with accurate laboratory calculations and conversions.
  • Demonstrated aptitude for managing reports.
  • Previous experience with writing SOPs preferred. 
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team. 
  • Able to carry out planned laboratory activities with minimal supervision.
  • Shows initiative to take on additional responsibility.
  • Proficient with Microsoft Office (Excel, Outlook, etc.).
  • Able to work flexible work hours to maintain critical testing during manufacturing runs.
  • Capable of working in a fast-paced environment and communicating effectively with a diverse work group.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment- Computer, printer, fax, and telephone.

Physical Demands-  

  • Frequent sitting, standing, walking
  • Carrying packages and moving bins and boxes, lifting up to 10 lbs.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients. 

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results. 

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 93+ industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission. 

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.


Responsibilities

  • Play an important role in process development projects assigned by leadership with the goal to implement and improve CAR-T, TILs and other T-cell therapies.  
  • Participate in the design, plan and execution of the experimental plan on process development to streamline the production of T-cell products for cancer immunotherapy. 
  • Take part in developing processes in alignment with regulatory rules and procedures applying to the generation and quality monitoring of cell therapy products to ensure rapid translation of developed procedures in the GMP lab. 
  • Take initiatives of troubleshooting problems as they arise in the lab and share best practices and lessons learned with the team. 
  • Play an important role in providing technical assessment of various new cell therapy technologies and make recommendations on process decisions for GMP implementation. 
  • Execute project deliverables to meet timelines. 
  • Maintain current knowledge of the field and introduce relevant materials to continuously improve the current processes.  
  • Maintain thorough accurate, legible, and organized written records, and electronic records. 
  • Produce written protocols and reports.  Prepare scientific presentations to report on the status of the work performed in the laboratory and speak in front of a group of scientists and management. 
  • Communicate effectively with lab members, manufacturing, analytical development and regulatory affairs.  
  • Interface with appropriate internal key stakeholders in partnerships 
  • Other duties as assigned. 

Qualifications/Skills

  • Ph.D. in a related scientific/engineering field preferred, or Masters degree with 5+ years’ experience in a related field, preferably in the biotech industry or equivalent combination of education and experience.
  • Experience in PD laboratory operations developing processes on various cell manufacturing platforms and closed systems for the development of T-cell therapy products.   
  • Strong knowledge in cell biology.  
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.  
  • Demonstrated strong communication skills, interpersonal skills and a superior drive for results. 
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff. 
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.  
  • Able to operate as an effective tactical, as well as strategic thinker. 
  • Able to coach and influence junior level scientists and associates.  
  • Able to work late nights, weekends, and holidays with very short advance notice.
  • Proficient with Microsoft Office Suite or related software.

Working Conditions, Equipment, Physical Demands 

Equipment- Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands- 

  • Occasional standing and walking required.
  • Frequent sitting, reaching, and computer/keyboard usage.
  • Occasional lifting, pushing, and pulling up to 10 lbs. required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now