Why Work Here?

Our mission at CTMC is to bridge the gap between the academic research environment, state of the art cell therapy development and manufacturing technology platforms, and leaders in clinical cancer care to enable rapid advancement of novel therapeutics from concept to clinic.

Our joint venture between MD Anderson Cancer Center, the world-renowned cancer center, and Resilience, a network of advanced biopharmaceutical solutions, creates a collaboration of cancer experts and state of the art development and manufacturing technologies. This unique business model has created a biotech-like engine within the prestigious Texas Medical Center so we can bring life-saving medicines more quickly and effectively to patients.

In this new era of precision medicine, we are shaping the direction of cancer treatment by combining the best talent from biotech and academia to create a dynamic and stimulating work environment with opportunities for growth – both personally and professionally. This drive and passion to create life-changing cancer treatments for patients is at the forefront of all that we do.

If you are seeking the next challenge with the desire to contribute to our unified goal of treating patients in their battle with cancer, contact CTMC at: hr@ctmc.com

Job Openings

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, located in the heart of the Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.   

Since inception in May 2022, our team has filed six INDs and have received approval, without delay, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.   

Our growing, state-of-the-art, 60,000 sq. ft. industrial facility in the Texas Medical Center is staffed by an integrated team of 94+ industry veterans and academic scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our organizational goals.   

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure to inspire professional growth and satisfaction. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission to accelerate cell therapies from bench to bedside for patients who need them. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission. 


Responsibilities

CTMC is looking for a highly motivated Project Manager with exceptional project management and communication skills to support the Project and Alliance Leadership team in Houston, TX. Project & Alliance Leadership (PAL) plays an important role in defining and delivering value to partners within the CTMC mission/portfolio. PAL serves as a centralized leadership function that aims to integrate CTMC’s deep technical and scientific expertise with operational capability to help create disruptive manufacturing solutions enabling impactful cell therapies to reach patients. In this role, you’ll be at the nexus of several of CTMC’s mission critical planning and execution work processes.  

 This role involves managing multiple GMP programs, requiring careful coordination with both external partners and internal stakeholders. You will act as the liaison with external partners to oversee the lifecycle of each GMP batch, from collection through disposition. Internally, you will lead the coordination of manufacturing, testing, and release timelines for GMP batches across all programs and modalities (TIL, CAR-T, and VV).

CTMC is continuously transferring technologies from development to operational functions. In this role, you will serve as a work process administrator for Technology Transfer across all programs (manufacturing processes, test methods, etc.) and modalities (TIL, CAR-T, and VV). You will define best practices and support Tech Transfer leads from both sending functions (PD, AD) and receiving functions (MFG, QC), ensuring smooth handovers of critical path activities.

Duties include but are not limited to:

  • Assisting with management of multiple programs in GMP production:
    • Serve as external interface with MD Anderson Cancer Center and biotech partners to coordinate starting material collections, provide visibility throughout manufacturing, and help plan finished drug product for disposition 
    • Maintain demand forecasts for all programs and then monitor and provide visibility to actual demand in real-time across GMP operations 
    • Serve as internal coordinator for production planning and scheduling across GMP operational functions including MFG, QC, and QA 
    • Develop and lead production tracking, establishing key metrics and managing partner deliverables to ensure timely and successful outcomes. 
    • Drive development and implementation of key manufacturing digital/information systems that enable better planning, scheduling, execution, and analysis of GMP operations 
  • Support project management of programs entering the GMP production phase to:
    • Serve as technology transfer workflow administrator by developing procedures and tools/templates (e.g. PFD, BOM/BOE, MBRs, trackers, etc.) to help standardize the transfer of critical process and analytical knowledge 
    • Support or lead the digitalization of test methods and manufacturing batch records through the implementation of an LIMS/MES and expanding its functionality 
    • Support technical (sending) and operational (receiving) leads during tech transfers by facilitating communication, coordination and the adoption of best practices and tools.
  • Other duties as required.

Qualifications/Skills

  • Bachelor’s degree in life science, or related field required
  • 7+ yr.’s. of relevant work experience, 1+ years of experience in cell therapy, production planning or closely related field or equivalent combination of education and experience preferred
  • Experience in academic and/or industrial cell therapy manufacturing or biologics manufacturing, preferred
  • Experience in early to late phase human therapeutic (drug) development 
  • Experience with both technical development and operations of advanced cell and gene therapies 
  • Experience interfacing with clinical site stakeholders 
  • Experience in cross-functional leadership roles 
  • Experience working in a fast-paced, collaborative team environment
  • Possess mindset focus on strategic thinking, data-driven decision making and effective communication
  • Proficient in Microsoft Outlook, Teams, Project, Excel, SharePoint, and PowerPoint

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment- Computer, printer, fax, and telephone.

Physical Demands- Prolonged periods of sitting at a desk and working on a computer and must be able to lift up to 15 pounds at times.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

Apply Now

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 93+ industry veterans and academic scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.

Responsibilities

  • Leads and oversees process development projects assigned by leadership with the goal to improve manufacturing processes for CAR-T, TILs and other T-cell therapies.  
  • Assess manufacturing processes supplied by prospective partner companies for suitability for GMP manufacture and identify any gaps.
  • Design, plan and oversee execution of the experimental plans to optimize/refine manufacturing process for T-cell therapeutics.
  • Manage, coach and develop reports.
  • Participate in hands-on project execution as needed, serve as a resource/subject matter expert for the technical team. Assign and manage reports to complete projects and trains junior team members on T-cell therapy processing. Troubleshoot technical issues with the team as they arise in the lab and share best practices and lessons learned. 
  • Develop processes in alignment with the latest FDA guidance and regulations applicable to the generation and quality monitoring of T-cell therapy products to ensure rapid translation of developed procedures in the GMP lab. 
  • Drive internal tech transfers from process development to manufacturing team. Lead the team to produce a complete draft of the manufacturing batch record aligned with CTMC quality standards at the conclusion of the development campaign and trains manufacturing operators in preparation for the engineering runs.
  • Provide technical assessment of various new cell therapy technologies and make recommendations on process decisions for GMP implementation. 
  • Coordinate execution of project deliverables to meet timelines. 
  • Maintain current knowledge of the T-cell manufacturing field and introduce relevant materials to continuously improve the current processes.  
  • Maintain thorough accurate, legible, and organized written and electronic records, including use of electronic lab notebook. 
  • Author or review protocols, technical reports and draft manufacturing batch records. Author or review process-related CMC sections of IND applications. Train team members on authorship of said documents and eventually delegates authorship.
  • Prepare scientific presentations to report on the status of the work performed in the laboratory and speak in front of a group of scientists and leadership that may include external partners .
  • Communicate effectively within the company with members of own team or other departments such as manufacturing, analytical development, quality control, regulatory affairs and project management.  
  • Interface with appropriate internal and external key stakeholders, work with other functions / departments to achieve project objectives.
  • Other duties as assigned.

Qualifications/Skills

  • Ph.D. in a related scientific/engineering field.
  • 10+ yrs. experience in PD laboratory operations developing processes on various cell manufacturing platforms and closed systems for the development of T-cell therapy products.   
  • Strong knowledge in T-cell biology.  
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team.  
  • Demonstrated strong communication skills, interpersonal skills and a superior drive for results. 
  • Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff. 
  • Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.  
  • Able to operate as an effective tactical, as well as strategic thinker. 
  • Able to coach and influence junior level scientists and associates.  
  • Flexible to work outside of normal business hours (nights, weekends) as needed.
  • Proficient with Microsoft Office Suite or related software.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office and lab environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer, printer, telephone
  • Laboratory equipment

Physical Demands-

  • Occasional standing and walking required.
  • Frequent sitting, reaching, and computer/keyboard usage.
  • Occasional lifting, pushing, and pulling up to 10 lbs. required.

The above job description is an overview of the functions and requirements for this position. This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

Apply Now

About CTMC

​CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, located in the heart of the Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.   

Since inception in May 2022, our team has filed six INDs and have received approval, without delay, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.   

Our growing, state-of-the-art, 60,000 sq. ft. industrial facility in the Texas Medical Center is staffed by an integrated team of 94+ industry veterans and academic scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our organizational goals.   

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure to inspire professional growth and satisfaction. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission to accelerate cell therapies from bench to bedside for patients who need them. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission. 


 Responsibilities

  • Perform routine and advanced flow cytometry experiments, including sample preparation, data acquisition, and data analysis.
  • Analyze flow cytometry data using specialized software and interpret results for both internal and external reports.
  • Participate in the development and optimization of new flow cytometry assays.
  • Provide technical expertise and training to other laboratory personnel and research teams as needed.
  • Support Flow Cytometry methods troubleshooting and investigations.
  • Accurately perform, analyze, and demonstrate proficiency on the following tests: Automated and manual cell counts and viability, ELISA, Molecular assays.
  • Perform analytical testing on cell and viral therapy products, to verify product quality, purity, and safety. 
  • Participate as an analyst in MQ activities including authoring SOPs and FRMs.
  • Demonstrate aseptic processing of samples for relevant tests.
  • Follow laboratory’s quality control policies and procedures. 
  • Document all quality control activities according to SOPs.  
  • Perform and document equipment maintenance and calibration activities according to SOPs.  
  • Assist in writing new SOPs, and revising SOPs for test methods, equipment maintenance, and general laboratory practices. 
  • Execute daily lab responsibilities and tasks to meet assigned schedule and deadlines. 
  • Perform stability testing as scheduled and specified in the stability studies or protocol for cell therapy and viral supernatant products. 
  • Assist in the execution of validation/qualification programs per ICH guidelines, cGMP and cGTP and other applicable standards. 
  • Reference material/standards characterization and trending. 
  • Assist area management to ensure that the lab is always in a state of readiness for a given area of relevant standards and regulations. 
  • Support inventory management for all QC lab activities. 
  • Maintain laboratory upkeep and organization.
  • Other duties as required. 

Qualifications/Skills

  • Bachelor’s degree in science field required or equivalent combination of education and experience.
  • 3+ years of hands-on experience with flow cytometry, preferably in a research or clinical laboratory setting required; 4-5+ years preferred.
  • Proficiency in operating flow cytometers (e.g., BD FACSLyric, Novocyte Advanteon, or similar instruments) and associated software (e.g., FlowJo, Kaluza, BD FACSuite).
  • Strong background in immunology, cell biology, and/or molecular biology.
  • Knowledge of LIMS software/system and previous experience using LIMS for product lot testing, EM and/or stability samples is a plus.
  • Excellent analytical skills with a strong attention to detail.
  • Ability to work independently and collaboratively in a fast-paced environment.
  • Experience with accurate laboratory calculations and conversions.
  • Previous experience with writing SOPs preferred. 
  • Demonstrated ability to collaborate effectively in a multi-disciplinary team. 
  • Able to carry out planned laboratory activities with minimal supervision.
  • Shows initiative to take on additional responsibility.
  • Proficient with Microsoft Office (Excel, Outlook, etc.).
  • Able to work flexible work hours to maintain critical testing during manufacturing runs.
  • Capable of working in a fast-paced environment and communicating effectively with a diverse work group.

Working Conditions, Equipment, Physical Demands 

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

  • Computer
  • Printer
  • Scanner
  • Telephone

Lab Equipment

Physical Demands-  

  • Frequent sitting, standing, walking
  • Carrying packages and moving bins and boxes, lifting up to 10 lbs.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act. 

The above job description is an overview of the functions and requirements for this position.  This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary. 

Apply Now